Fc or not Fc; that is the question: Antibody Fc-receptor interactions are key to universal influenza vaccine design
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Fc or not Fc; that is the question: Antibody Fc-receptor interactions are key to universal influenza vaccine design.
A universal vaccine that provides long-lasting protection from both epidemic and pandemic influenza viruses remains the "holy grail" of influenza vaccine research. Though virus neutralization assays are the current benchmark of measuring vaccine effectiveness, it is clear that Fc-receptor functions can drastically improve the effectiveness of antibodies and vaccines in vivo. Antibodies that kil...
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ژورنال
عنوان ژورنال: Human Vaccines & Immunotherapeutics
سال: 2017
ISSN: 2164-5515,2164-554X
DOI: 10.1080/21645515.2017.1290018